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CJC-1295 with drug affinity complex. 5mg lyophilized powder per vial.
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CJC-1295 (DAC)
What It Is
CJC-1295 with DAC is the long-acting version. The "Drug Affinity Complex" is a chemical modification that lets it bind permanently to albumin in your blood, extending the half-life from 30 minutes to 5-8 days. One injection raises GH and IGF-1 for a full week. The tradeoff: you lose the pulsatile pattern and get sustained elevation instead.
How It Works
After injection, the DAC modification forms a permanent chemical bond with albumin (a blood protein). This prevents the kidneys from clearing it and protects it from enzymes. The result is continuous GHRH receptor stimulation for days rather than minutes. Your pituitary keeps getting the "release GH" signal around the clock, producing a sustained but less pulsatile elevation.
What The Research Shows
Single dose elevated GH levels for 6-8 days — confirmed in pharmacokinetic studies.
IGF-1 increased 1.5-3x over baseline with weekly dosing.
The sustained pattern is different from natural GH pulsing — whether this matters for outcomes is still debated in the research community.
Sources
Prolonged stimulation of growth hormone and insulin-like growth factor I secretion by CJC-1295
Teichman SL et al. — J Clin Endocrinol Metab, 2006 · PubMed
Information derived from published preclinical and clinical research. Provided for educational purposes only — not medical advice.
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