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Long arginine 3 insulin-like growth factor. 1mg lyophilized powder per vial.
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IGF-1 LR3
What It Is
IGF-1 LR3 is a modified version of IGF-1 — the growth factor your liver produces in response to growth hormone. The modifications (arginine at position 3 + 13-amino acid extension) make it 2-3x more potent than natural IGF-1 by preventing it from being bound up by binding proteins. While HGH tells your body to produce IGF-1, this compound IS IGF-1 — it skips the middleman.
How It Works
Activates the IGF-1 receptor directly, triggering the PI3K/Akt pathway (cell survival, protein synthesis) and MAPK/ERK pathway (cell proliferation). Because it doesn't bind to IGF binding proteins like native IGF-1, more of it stays active in circulation — half-life extends from 20 minutes to 20-30 hours. It drives muscle satellite cell activation, protein synthesis, and inhibits cell death.
What The Research Shows
Stimulates cell growth and protein synthesis at lower concentrations than native IGF-1.
Activates muscle satellite cells — the stem cells responsible for muscle repair and growth.
Extended half-life (20-30 hours vs 20 minutes for native IGF-1) means sustained biological activity.
Promotes wound healing through enhanced cell migration and proliferation.
Sources
The insulin-like growth factor system and its biological actions
Clemmons DR — Endocrinol Metab Clin North Am, 2012 · PubMed
Information derived from published preclinical and clinical research. Provided for educational purposes only — not medical advice.
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