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Selective GH secretagogue. 5mg lyophilized powder per vial.
All compounds independently tested and verifiedLab results →
Ipamorelin
What It Is
Ipamorelin is the cleanest GH secretagogue available. It's a ghrelin mimetic that triggers GH release without the side effects that plague older compounds like GHRP-6 and GHRP-2. No cortisol spike. No prolactin spike. No ravenous hunger. Just GH release. That selectivity profile is why it's become the default choice in most GH peptide protocols.
How It Works
It activates the ghrelin receptor (GHSR1a) on your pituitary — the same receptor the hunger hormone ghrelin uses. But ipamorelin is selective enough that it triggers GH release without significantly activating the appetite, cortisol, or prolactin pathways that ghrelin normally hits. Combined with CJC-1295 (No DAC), it creates an amplified GH pulse through two complementary receptor pathways.
What The Research Shows
Produces strong GH release with minimal effects on cortisol, prolactin, or other hormones — the cleanest profile of any GHRP.
In direct comparison with GHRP-6, ipamorelin matched GH output but without the ACTH and cortisol spikes.
Phase 2 trials investigated it for post-surgical recovery — it accelerated return of bowel function after surgery.
The go-to pairing with Mod-GRF (CJC-1295 No DAC) produces synergistic GH release exceeding either compound alone.
Sources
Ipamorelin, the first selective growth hormone secretagogue
Raun K et al. — Eur J Endocrinol, 1998 · PubMed
Information derived from published preclinical and clinical research. Provided for educational purposes only — not medical advice.
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