- Purity
- 99.8%
- Method
- LC-MS
- Tested
- 2026-09-08
In Stock
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Melanotan-2 acetate. 10mg lyophilized powder per vial.
VERIFICATION โ Batch MT2824ALF
All compounds independently tested and verifiedLab results โ
Melanotan-2
What It Is
Melanotan-2 is a non-selective melanocortin agonist โ it hits MC1R through MC5R receptors all at once. The results: tanning without UV exposure (MC1R), appetite suppression (MC4R), and increased sexual arousal (MC4R). PT-141 was actually derived from MT-2 by making it more selective. MT-2 gives you the whole package, which is either a feature or a bug depending on what you're after.
How It Works
MC1R activation โ melanogenesis (tanning). MC3R โ energy homeostasis. MC4R โ appetite suppression AND sexual arousal. MC5R โ exocrine function. Because MT-2 hits all of these, you get multiple effects simultaneously. The tanning is UV-independent โ melanocytes produce eumelanin (dark pigment) without sun exposure.
What The Research Shows
Produced significant skin darkening in fair-skinned individuals without UV exposure.
The sexual arousal effects led to the development of PT-141 as a more targeted derivative.
Appetite suppression is dose-dependent โ MC4R-mediated.
Common side effects: nausea, facial flushing, fatigue โ typically dose-dependent and transient.
Sources
Subcutaneous administration of Melanotan II for skin tanning
Dorr RT et al. โ Clin Pharmacol Ther, 1996 ยท PubMed
Information derived from published preclinical and clinical research. Provided for educational purposes only โ not medical advice.
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