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Nicotinamide adenine dinucleotide. 100mg lyophilized powder per vial.
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NAD+
What It Is
NAD+ is the molecule behind the entire longevity research boom. It's a coenzyme in every cell involved in 500+ enzymatic reactions — energy production, DNA repair, gene expression, you name it. The problem: your NAD+ levels drop roughly 50% between ages 40 and 60. That decline is now considered a root cause of age-related disease, not just a symptom of it. Injectable NAD+ achieves complete, immediate repletion — oral supplements can't match the bioavailability.
How It Works
NAD+ fuels three critical enzyme families: sirtuins (the "longevity genes" — they regulate metabolism and stress response), PARPs (DNA repair enzymes), and CD38 (immune signaling). When NAD+ drops, all three systems underperform. DNA damage accumulates, mitochondria dysfunction, metabolism slows, and inflammation increases. Restoring NAD+ levels restores function across all three pathways simultaneously.
What The Research Shows
NAD+ supplementation in aged mice restored mitochondrial function and exercise capacity — old mice performed like young ones.
Sirtuin activation via NAD+ improved insulin sensitivity, reduced inflammation, and extended lifespan across multiple species.
In neurodegeneration models, NAD+ reduced neuronal death and improved cognitive function.
IV NAD+ achieves rapid, complete repletion that oral NMN/NR supplements can't match due to absorption limitations.
Sources
NAD+ metabolism and its roles in cellular processes during ageing
Covarrubias AJ et al. — Nat Rev Mol Cell Biol, 2021 · PubMed
Information derived from published preclinical and clinical research. Provided for educational purposes only — not medical advice.
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