- Purity
- 98.8%
- Tested
- 2026-06-09
In Stock
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Nootropic heptapeptide. 10mg lyophilized powder per vial.
VERIFICATION โ Batch 2026-05 / SX10731PTR1
- Purity
- 99.8%
- Method
- HPLC + LC-MS
- Tested
- 2026-10-13
All compounds independently tested and verifiedLab results โ
Semax
What It Is
Semax is a nootropic peptide derived from ACTH (the stress hormone precursor) but without any of the stress or cortisol effects. Developed in Russia and approved there as a pharmaceutical since the 1990s, it's been studied for cognitive enhancement, neuroprotection, and focus. It increases BDNF โ the protein responsible for growing new neurons and strengthening existing connections.
How It Works
Semax boosts BDNF (brain-derived neurotrophic factor), NGF (nerve growth factor), and TrkB receptor signaling โ the three pillars of neuroplasticity. More BDNF = better learning, memory consolidation, and neural repair. Despite being derived from ACTH, the modifications completely eliminate steroidogenic activity โ your cortisol stays untouched.
What The Research Shows
Increases BDNF expression in the hippocampus and cortex โ the brain regions responsible for memory and higher cognition.
In stroke models, it reduced brain damage when given within the acute treatment window.
Clinical studies showed improved attention, memory, and cognitive function in patients with cerebrovascular disease.
No cortisol effects despite being derived from ACTH โ clean nootropic profile.
Sources
Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus
Dolotov OV et al. โ Brain Res, 2006 ยท PubMed
Information derived from published preclinical and clinical research. Provided for educational purposes only โ not medical advice.
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