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For in vitro laboratory research use only. Not for human consumption. All products are supplied strictly for in vitro laboratory research use only. Not drugs, foods, supplements, or cosmetics. Not evaluated by Health Canada or the FDA.
Dose per Vial
10mg
Sold As
Single vial
Form
Lyophilized powder
Storage
2โ€“8ยฐC
Price
$39.99 CAD

Mitochondrial-derived peptide. 10mg lyophilized powder per vial.

VERIFICATION โ€” Batch 20260302-01

All compounds independently tested and verifiedLab results โ†’


Also Available

Other Doses

20mg40mg

Research

MOTS-c


What It Is

MOTS-c is a peptide your mitochondria produce โ€” not your DNA, your mitochondria. That alone makes it unusual. Discovered in 2015, it acts as an exercise mimetic โ€” it activates many of the same metabolic pathways that exercise does. Think of it as your mitochondria sending a signal to the rest of your body saying "we need to burn more fuel and build more capacity."

How It Works

MOTS-c activates AMPK, the master energy sensor in every cell. AMPK activation promotes glucose uptake, fat burning, and mitochondrial biogenesis โ€” the same things exercise triggers. Under metabolic stress, MOTS-c actually moves from the mitochondria into the cell nucleus to directly regulate gene expression. Circulating levels decline with age, correlating with metabolic dysfunction.

What The Research Shows

01

MOTS-c prevented obesity and insulin resistance in mice fed a high-fat diet โ€” without changing their food intake.

02

It improved exercise performance in both young and old mice โ€” genuine exercise mimetic effects.

03

Levels decline with age and are inversely correlated with metabolic disease markers.

04

Human muscle cell studies confirmed it enhances glucose uptake and metabolic flexibility.

Sources

MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline

Reynolds JC et al. โ€” Nat Commun, 2021 ยท PubMed

Information derived from published preclinical and clinical research. Provided for educational purposes only โ€” not medical advice.

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For in vitro laboratory research use only. Not for human consumption. All products are supplied strictly for in vitro laboratory research use only. Not drugs, foods, supplements, or cosmetics. Not evaluated by Health Canada or the FDA. By purchasing, you confirm compliance with all applicable laws and regulations.