- Purity
- 99.89%
- Tested
- 2026-06-29
Currently Unavailable
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Triple agonist (GIP/GLP-1/glucagon). 40mg lyophilized powder per vial.
VERIFICATION โ Batch 2026-06-20
All compounds independently tested and verifiedLab results โ
Retatrutide
What It Is
Retatrutide is the triple threat โ it hits GIP, GLP-1, AND glucagon receptors all at once. It's the first triple agonist to reach large clinical trials. The glucagon piece is the game-changer: it ramps up your body's energy expenditure and forces your liver to burn more fat. Early trial data produced the highest weight loss numbers ever seen in a controlled study.
How It Works
Three receptors, three effects. GLP-1 kills your appetite and slows digestion. GIP improves fat cell metabolism and insulin handling. Glucagon โ the new addition โ tells your liver to burn fat for fuel and cranks up thermogenesis (heat production = calories burned). The glucagon component is why retatrutide may cause more weight loss than even tirzepatide โ it literally increases how many calories you burn at rest.
What The Research Shows
Phase 2 data showed up to 24.2% weight loss at 48 weeks at the highest dose โ the most ever recorded in a controlled obesity trial at publication.
Up to 86% of participants normalized their liver fat levels. That's an extraordinary result for fatty liver.
Currently in Phase 3 trials (TRIUMPH program). If results hold, this becomes the most potent weight loss compound available.
Side effects are similar to other GLP-1 drugs โ mostly GI (nausea, diarrhea), worst in the first weeks, improving with dose titration.
Sources
Triple-Hormone-Receptor Agonist Retatrutide for Obesity
Jastreboff AM et al. โ N Engl J Med, 2023 ยท PubMed
Information derived from published preclinical and clinical research. Provided for educational purposes only โ not medical advice.
Customer Reviews
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Great communication when a product came back in stock and even got a free bottle of bac water!
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Product quality is the best and had it delivered to my office within 72 hours of ordering.
